Not crazy different but not crazy The principle is correct but its the execution that will be a challenge.
I think the normal way to look at this is to pick a set of combinations, say 100, then eliminate all the BAD ones so you may be left with 60-70. After you have the 60-70 you may want to see if any of them have hit before - that might be worthwhile.
If you apply all the filters for all the combos, I think you might still end up with a few million combinations left - then what?
But even much better is to check out the best bet numbers and pool sets in the lotto 649 predictions that are posted by the members here .. you will find some amazingly accurate combos that do not require you to fill out 13 million plus ticket slips